Risk factors/symptoms of DVT

Risk factors/symptoms of DVT

The causes of deep venous thrombosis can be hereditary or acquired and can occur as a result of alterations in blood flow, vascular endothelial injury, or hypercoagulable states.

Some risk factors that put patients at risk for acquiring a DVT include prolonged bed rest or hospitalizations, pregnancy, age >65, history of stroke, family history of VTE, oral contraceptives, smoking, recent surgery, malignancy, prior thromboembolisms, extended travel, trauma, obesity, or recent infection.

Inherited risk factors of developing a DVT include hypercoagulability and thrombophilia, such as defects in protein S, protein C, and antithrombin, factor V Leiden mutation, and prothrombin gene mutation. DVT’s should be suspected in patients who present with leg swelling, pain, warmth, and erythema. Typically, symptoms are unilateral and are confined to the calf, however patients can experience symptoms in the entire leg. 


Bauer, K. (2021, July 20). Clinical presentation and diagnosis of the nonpregnant adult with suspected deep vein thrombosis of the lower extremity. UpToDate. Retrieved March 2, 2022

This article reviewed by Dr. Jim Liu, MD and Ms. Deb Dooley, APRN.

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